Abstract Hypoxia promotes aggressive tumor phenotypes and mediates the recruitment of suppressive T cells in invasive breast carcinomas.We investigated the role of hypoxia in relation to T-cell regulation in ductal carcinoma in situ (DCIS).We designed a deep learning system tailored for the tissue architecture complexity of DCIS, and compared pure
In practice and despite Anfinsen’s dogma, the refolding of recombinant multiple SS-bonded proteins is famously difficult because misfolded species with non-native SS-bonds appear upon the oxidization of their cysteine residues.On the other hand, single SS-bond proteins are thought to be simple to refold because their cysteines have only one S
Miao silver, generally referred to as the unique silver ornaments manufactured by the Miao ethnicity with over 400 years of history, was listed as a Chinese national intangible cultural heritage in 2006.Through primary research methods, including local investigation, interviews, and workshops at Maliao Village in Guizhou, this study found that size
In the present work, direct numerical simulation data of a laboratory-scale high Karlovitz number (Ka) jet flame with a strong mean shear and a high Ka freely propagating planar flame without a girls hoody mean shear were analyzed to explore the influence of flame orientation and mean shear on flame stretch in highly turbulent flames.Three flame fr